Herpes Cure Pipeline 5.0

The 5th annual edition

Herpes Cure
Pipeline 5.0

Our annual report tracking the therapies and vaccines in development for herpes simplex virus. The poster is out now. Join the researchers live on October 7 for the full release.

The Herpes Cure Pipeline 5.0 poster, charting selected preclinical research and clinical development programs for herpes simplex virus from Phase 1 trials through FDA review, with an executive summary of updates since Pipeline 4.0.View full size
Presented at the 2026 STI Prevention Conference · Atlanta, August 31 – September 2, 2026
The poster

The 2026 pipeline at a glance

Pipeline 5.0 maps the programs working toward a cure for herpes simplex virus, from preclinical research to FDA review, and tracks what has changed since last year’s edition.

1Under FDA review
5In Phase 1–2 clinical trials
5Preclinical programs of interest

Key updates since Pipeline 4.0

  • Antivirals are advancing. Every antiviral drug in clinical development in Pipeline 4.0 has moved forward.
  • Two vaccines were discontinued. Development stopped on two vaccine candidates that were in clinical development in Pipeline 4.0.
  • A preclinical bottleneck. Little progress in the preclinical programs from Pipeline 4.0, and very few new approaches added or advanced.

Poster authorsArjun P. Vij, BS · Jeffrey D. Klausner, MD, MPH · Lao-Tzu Allan-Blitz, MD, MPH · Luis M. Schang, MV, PhD · Gary Richwald, MD, MPH

Live release event

Hear it from the researchers

On Wednesday, October 7 at 3:00 PM ET, the team behind Pipeline 5.0 walks through the 2026 findings live on Zoom: which programs advanced, which stalled, and where the field goes next. Bring your questions.

Save my seat
Dr. Jeffrey Klausner

HCA President

Jeffrey D. Klausner

MD, MPH

Clinical Professor of Medicine and Public Health, Keck School of Medicine of USC

Dr. Lao-Tzu Allan-Blitz

HCA Secretary & Treasurer

Lao-Tzu Allan-Blitz

MD, MPH

Assistant Professor of Medicine, UCLA David Geffen School of Medicine

Dr. Luis Schang

HCA Board Member

Luis M. Schang

MV, PhD

Professor of Chemical Virology, Cornell University; President, International Society for Antiviral Research

The 5.0 rollout

Out now, and what’s next

  1. Released

    The poster

    First presented at the 2026 STI Prevention Conference in Atlanta.

    See the poster
  2. October 7, 2026

    Live release event

    The researchers present the full Pipeline 5.0 findings on Zoom.

    Register
  3. Coming soon

    Full slide deck

    The complete Pipeline 5.0 slides will be posted on this page after the release.

October 7 · Live on Zoom

Be there when Pipeline 5.0 is released

Wednesday, October 7 · 3:00 PM ET / 12:00 PM PT
Free and open to everyone.